Crystal structure of the catalytic domain of human PARP1 in complex with olaparib
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Crystal structure of the catalytic domain of human PARP1 in complex with olaparib Descriptor: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, Poly [ADP-ribose] polymerase 1, SULFATE ION Authors: Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. Deposit date: 2020-09-04 Release date: 2021-01-13 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res., 49, 2021
创建时间：
2020-09-04
