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Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of HD

ChEBI2011-11-01 更新2026-07-21 收录

亨廷顿病动物模型

基因表达纵向分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-32417 数据链接链接失效反馈

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资源简介：

Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of HD

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创建时间：

2011-11-01

亨廷顿病动物模型

HDAC抑制剂

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by a late clinical onset of psychiatric, cognitive, and motor symptoms. Transcriptional dysregulation is an e

NIAID Data Ecosystem90

Analysis of differential gene expression in the striatum of R6/2 Huntington's disease model vs. control mice

亨廷顿病动物模型

神经细胞转录组学

5 mice per group of each: R6/2 and isogenic wild-type controls. Overall design: Total RNA was isolated and sequenced from the striatum of R6/2 HD model and Control mice (11 weeks of age).

NIAID Data Ecosystem40

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates.

亨廷顿病动物模型

线粒体能量代谢障碍

Although the gene defect responsible for Huntington disease (HD) has recently been identified, the pathogenesis of the disease remains obscure. One potential mechanism is that the gene defect may lead

PubMed Central1995-07-18 更新20

Differences in durations and gradients of transitions to wake for each frequency band between normal and HD transgenic sheep.

睡眠脑电图

亨廷顿病动物模型

Differences in durations and gradients of transitions to wake for each frequency band between normal and HD transgenic sheep.

NIAID Data Ecosystem80

Longitudinal RSfMRI in zQ175 DN mouse model of Huntington's Disease - Part I

亨廷顿病动物模型

静息态脑功能

This is a longitudinal project in resting-state fMRI across different ages of the zQ175DN HET mouse model of Huntington's disease and age-matched controls. This data set has been used in the following

Mendeley Data30

Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of HD

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