相关数据集
PCBP1/2 and TDP43 Function As NAT10 Adaptors In ac4C Writer Complex Towards mRNAs in Mammalian Cells
Massive numbers of modified bases in mRNAs sculpt the epitranscriptome and play vital roles in RNA metabolism. The only known acetylated RNA modification, N-4-acetylcytidine (ac4C), is highly conserve
NIAID Data Ecosystem60
8-oxoG RNA IP data set 2: Air pollution mixture derived from the reaction of 100 ppb acrolein, 97 ppb methacrolein, 44 ppb alpha-pinene and 100 ppb O3 for 1.5 h
While environmental agents such as air pollution have been shown to be causative to diseases, yet limited knowledge exist on their mechanism of action. Here we used RNA-sequencing in combination with
NIAID Data Ecosystem30
Replication Data for “Deregulating m6A Regulators Leads to Altered RNA Biology in Glioma Cell Lines”
This dataset accompanies the study “Deregulating m6A Regulators Leads to Altered RNA Biology in Glioma Cell Lines”. It examines how perturbation of key m6A RNA regulators—METTL3 (writer), ALKBH5 (eras
NIAID Data Ecosystem20
Deep and accurate detection of m6A RNA modifications in human and mouse cells using miCLIP2 and m6Aboost machine learning [b]
N6-methyladenosine (m6A) is the most abundant internal RNA modification in eukaryotic mRNAs and influences many aspects of RNA processing, such as RNA stability and translation. miCLIP (m6A individual
NIAID Data Ecosystem30
Direct RNA sequencing enables single-nucleotide m6A detection in endogenous transcript isoforms
We report the direct RNA sequencing of HEK293 and a primary human mammary epithelial cell (HMEC) line using Oxford Nanopore based sequencing. Using this data, we built an algorithm to detect m6A modif
NIAID Data Ecosystem30
