Crystal structure of Patched-1 ectodomain 2 (PTCH1-ECD2) in complex with nanobody 75
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Crystal structure of Patched-1 ectodomain 2 (PTCH1-ECD2) in complex with nanobody 75 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody NB75, Protein patched homolog 1, ... Authors: Rudolf, A.F, Kowatsch, C, El Omari, K, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. Deposit date: 2019-05-31 Release date: 2019-10-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
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2019-05-31
