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Structurally Defined α‑Tetralol-Based Chiral Hypervalent Iodine Reagents

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NIAID Data Ecosystem2026-03-11 收录
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A novel class of chiral hypervalent iodine reagents containing an α-tetralol scaffold is introduced. Iodine triacetate is employed in a key step as a highly selective and efficient iodinating reagent for a short and convenient synthesis of iodine­(III) derivatives. Solid-state X-ray analyses offer valuable structural information, while reactivities and stereoselectivities are investigated in three model reactions.

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2019-06-09
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