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Phosphoproteomics of patient-derived neurons identifies targets and markers associated with mutations in the PLPPR4 gene

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Induced pluripotent stem cells (iPSCs) were generated from peripheral blood cells of a patient with ID and differentiated into neurons. Label-free phosphoproteomics was used to assess the phosphorylation of proteins in neurons derived from both patients and healthy controls.

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2024-10-23
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