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Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase (PRMT5) Inhibitors

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase (PRMT5) Inhibitors Descriptor: 1,2-ETHANEDIOL, 2-[[7-[(2~{R},3~{R},4~{S},5~{R})-5-[(~{R})-(4-chlorophenyl)-oxidanyl-methyl]-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidin-4-yl]amino]ethanal, DIMETHYL SULFOXIDE, ... Authors: Tong, S, Lin, H. Deposit date: 2019-05-12 Release date: 2019-06-19 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors. Acs Med.Chem.Lett., 10, 2019
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2019-05-12
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