Metabolites in MW and DM extracts from the mouse liver that were significantly different between the normal and UVB groups after 6 weeks and were tentatively identified using UPLC-Q-TOF-MS analysis.

Variables were selected by VIP value (>0.7) and p-value (<0.05) from OPLS-DA model.
MW; MeOH/water extracts, DM; dichloromethane/MeOH extracts.
FA; formic acid, LysoPC; lysophosphatidylcholine, LysoPE; lysophosphatidylethanolamine.
atR was retention time.
bAssignment of metabolites contributing to the observed variance was performed by elemental composition analysis software with calculated mass, mass tolerance (mDa and ppm), double bond equivalent (DBE), and the iFit algorithm was implemented in the MassLynx, and by either commercial standard compounds compared with the retention time and mass spectra or HMDB (The Human Metabolome Data Base (http://www.hmdb.ca/)).
cM.W.; molecular weight.
dFold change was calculated by dividing the mean of the peak intensity of each metabolite from UVB group relative to normal group.
eVIP, variable important in the projection.
*Asterisk means the two forms of lysoPC, with the fatty acyl groups at positions 1 (sn-1) or 2 (sn-2) on the glycerol backbone.
#Cholic acid derivatives with taurine were not successfully identified, but it was predicted to be one of the following compounds: taurocholic acid, taurallocholic acid, tauro-b-muricholic acid, taurohyocholate, or tauroursocholic acid.
§Deoxycholic acid derivatives with taurine were not successfully identified, but it was predicted to be one of compounds such as tauroursodeoxycholic acid, taurodeoxycholic acid ortaurochenodesoxycholic acid.
Metabolites in MW and DM extracts from the mouse liver that were significantly different between the normal and UVB groups after 6 weeks and were tentatively identified using UPLC-Q-TOF-MS analysis.