Rapid Idiosyncratic Mechanisms of Clinical Resistance to KRAS G12C Inhibition
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https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002734.v1.p1
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Using deep RNA and whole exome sequencing of pre- and post-treatment autopsy samples, we reveal diverse clonal populations that occurred through altered cell intrinsic, tumor microenvironment and immunologic remodeling mechanisms of resistance.]]>
Deceased lung cancer patient treated at UNC hospitals]]>
创建时间：
2021-12-15
