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Rapid Idiosyncratic Mechanisms of Clinical Resistance to KRAS G12C Inhibition

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NIAID Data Ecosystem2026-04-30 收录
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Using deep RNA and whole exome sequencing of pre- and post-treatment autopsy samples, we reveal diverse clonal populations that occurred through altered cell intrinsic, tumor microenvironment and immunologic remodeling mechanisms of resistance.]]> Deceased lung cancer patient treated at UNC hospitals]]>

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2021-12-15
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