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Phosphorylation controls mRNA retention via nuclear speckle cohesion during environmental perturbations. Phosphorylation controls mRNA retention via nuclear speckle cohesion during environmental perturbations

NIAID Data Ecosystem2026-05-01 收录

转录后调控

细胞应激响应

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1005649 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2023-08-15

环状RNA-蛋白质相互作用

转录后调控

The exon junction complex (EJC) is a central effector of mRNAs fate, linking nuclear processing to mRNA transport, translation and surveillance. Little is known about its transcriptome-wide targets. W

NIAID Data Ecosystem100

A global survey of small RNA interactors identifies KhpA and KhpB as major RNA-binding proteins in Fusobacterium nucleatum

细菌RNA结合蛋白

转录后调控

The common oral microbe Fusobacterium nucleatum has recently gained attention when it was found to colonize tumors throughout the human body. Fusobacteria are also interesting in regard to bacterial R

NIAID Data Ecosystem60

Expression data from DP cells in the thymus of SRSF1-null and wild type mice

iNKT细胞发育

转录后调控

iNKT cells are highly conserved innate-like T lymphocytes that develop from CD4+CD8+ DP cells. It remains largely unknown whether post-transcriptional regulation has critical roles in iNKT cells. Here

NIAID Data Ecosystem40

Role of the mRNA-binding protein HuR in the global transcriptomic status of cells stimulated with electrophiles and oxidants

转录组学分析

细胞应激响应

HuR has been implicated as a stress-responsive protein: cytoplasmic translocation of HuR is promoted by several small-molecule stressors, e.g., H2O2, arsenite, and the cyclopentenone prostaglandin A2

NIAID Data Ecosystem70

HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA. HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA

肌生成调控

转录后调控

Our study delineates a novel mechanism for HuR-mediated posttranscriptional regulation of myogenesis that requires its association to YB1 and provides new insights into the central role of posttranscr

NIAID Data Ecosystem40

Phosphorylation controls mRNA retention via nuclear speckle cohesion during environmental perturbations. Phosphorylation controls mRNA retention via nuclear speckle cohesion during environmental perturbations

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