Inhibition of Jag2-mediated Notch1 signaling by Notch1 antibodies.
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https://figshare.com/articles/dataset/_Inhibition_of_Jag2_mediated_Notch1_signaling_by_Notch1_antibodies_/535976
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资源简介:
aLBD: EGF-like repeats (1–13) encompassing the ligand-binding domain; NRR: Negative regulatory region.
bFACS score on Notch1 expressing HEK cells: MFI<100 (+); MFI 100–500 (++); MFI 501–1000 (+++); MFI>1000 (++++); MFI = Mean Fluorescence Intensity.
cCo-culture assay with Notch1-Gal4 T-REX-U2OS cells transfected with UAS-luciferase reporter and Flp-In-3T3-Jag2 cells; normalized to signal obtained with Flp-In-3T3 parental cell line; average and standard deviation from at least 4 independent experiments.
创建时间:
2010-02-08



