For each GWAS coronary artery disease (CAD) locus, we report the number of variants in linkage disequilibrium (LD) for which we designed (Variants designed) and experimentally tested (Variants tested) at least 2 sgRNAs.

The Variant saturation number is caculated by dividing Variants tested by Variants designed. "1" in the column Locus with 1 hit indicated that at least one of the variants tested was significant in the CRISPR screens. For each GWAS locus, we list the total number and identifiers of the hits in the CRISPR screens. We report the closest genes and the assigned biological pathways based on Klarin et al, Nature Genetics, 2017.
(XLSX)