Gene expression in drug resistant and circulating tumor cell cultured H460 or A549 cells Overall design: mRNA expression profiles of 2-dimensionally cultured and circulating tumor cell cultured H460 a
NAD(P)H:quinone oxidoreductase 1 (NQO1) has been shown to be a potential therapeutic target for various human diseases, such as cancer and neurodegenerative disorders. Recent advances in computation
In this paper, we applied an innovative nuclear magnetic resonance (NMR)-guided screening and ligand design approach, named focused high-throughput screening by NMR (fHTS by NMR), to derive potent, lo