BACE-1 in complex with compound #22
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BACE-1 in complex with compound #22 Descriptor: Beta-secretase 1, N-{3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl}-5-methoxypyrazine-2-carboxamide, SULFATE ION Authors: Hendle, J, Timm, D.E, Stout, S.L. Deposit date: 2021-05-21 Release date: 2021-07-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor. J.Med.Chem., 64, 2021
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2021-05-21
