Crystal structure of BRD4-BD1 bound with DI106
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Crystal structure of BRD4-BD1 bound with DI106 Descriptor: (3~{R})-6-[[4-(3,5-dimethyl-1~{H}-pyrazol-4-yl)pyrimidin-2-yl]amino]-1,3-dimethyl-4-propan-2-yl-3~{H}-quinoxalin-2-one, Isoform C of Bromodomain-containing protein 4 Authors: Cao, D, Xiong, B. Deposit date: 2023-10-12 Release date: 2024-07-24 Last modified: 2025-02-19 Method: X-RAY DIFFRACTION (1.13 Å) Cite: Structure-Based Rational Design and Evaluation of BET-Aurora Kinase Dual-Inhibitors for Treatment of Cancers. J.Med.Chem., 68, 2025
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2023-10-12
