PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis

NIAID Data Ecosystem2026-05-01 收录

坏死性凋亡调控

蛋白质相分离

数据链接：

https://data.mendeley.com/datasets/ypj5p7jrsv 数据链接链接失效反馈

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资源简介：

This data-set is original uncropped blots for a manuscript that is under consideration for Molecular Cell.

创建时间：

2023-11-06

Lipid mediated–phase separation of AGO proteins on ER controls nascent peptide ubiquitination

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基因表达调控

AGO/miRNA-mediated gene silencing and ubiquitin-mediated protein quality control represent two fundamental mechanisms that control proper gene expression. Here we unexpectedly discover that fly and hu

doi.org160

Autocrine IL6 activates the STAT3-DNMT axis to silence the TNFa-RIP1 necroptosis pathway to sustain myeloid-derived suppressor cell survival and accumulation

肿瘤免疫微环境

坏死性凋亡调控

Massive accumulation of myeloid-derived suppressor cells (MDSCs) is a hallmark of cancer. It is well-known that proinflammatory mediators induce MDSC accumulation. However, the functions of cell death

NIAID Data Ecosystem50

Hydrophobicity of arginine leads to reentrant liquid-liquid phase separation behaviors of arginine-rich proteins

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生物工程

Intrinsically disordered proteins rich in cationic amino acid groups can undergo Liquid-Liquid Phase Separation (LLPS) in the presence of charge-balancing anionic counterparts. Arginine and Lysine are

Figshare2022-11-09 更新20

Molecular condensation of the CO/NF-YB/NF-YC/FT complex gates floral transition in Arabidopsis

花发育分子调控

蛋白质相分离

The plant master photoperiodic regulator CONSTANS (CO) interacts with Nuclear Factor-Y subunits B2 (NF-YB2) and C9 (NF-YC9) and transcriptionally activates the florigen gene FLOWERING LOCUS T (FT), re

NIAID Data Ecosystem60

A selective autophagy pathway for phase separated endocytic protein deposits. Wilfling et al.

细胞自噬机制

蛋白质相分离

Raw data of westernblot gels, Coomassie stained gels, and microscopy images

NIAID Data Ecosystem30