Imaging mass cytometry single-cell atlas of follicular lymphoma (processed data)
收藏资源简介:
Processed, de-identified single-cell data from imaging mass cytometry (IMC, Hyperion) of follicular lymphoma tissue microarrays, accompanying the manuscript "Spatial Proteomics Reveals Dual-Compartment Immune Evasion Architecture and Core Lymphomagenic Stromal Niches in Follicular Lymphoma" (Elemento et al.). Two AnnData (.h5ad) files contain the analysis-ready single-cell tables for two complementary 39-marker antibody panels (T, immune-focused; S, stromal/myeloid-focused) across four tissue microarrays, totaling ~4.2 million cells with cell-type annotations, spatial coordinates, and cross-TMA embeddings. The .X matrix is arcsinh(raw/5)-transformed and per-marker z-scored. See the included README for the full data dictionary, processing provenance, and checksums. Raw pixel/image data and patient-level clinical data are not included in this deposit (see the manuscript Data Availability statement). Analysis code: https://github.com/oelemento/IMC-FL .



