The open state mouse TRPM8 structure in complex with the cooling agonist C3, AITC, and PI(4,5)P2

The open state mouse TRPM8 structure in complex with the cooling agonist C3, AITC, and PI(4,5)P2 Descriptor: 3-isothiocyanatoprop-1-ene, CALCIUM ION, Transient receptor potential cation channel subfamily M member 8, ... Authors: Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. Deposit date: 2022-08-18 Release date: 2022-10-26 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022