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Genome sequence of non-deacetylated poly-N-acetylglucosamine-hyperproducing Staphylococcus aureus

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NIAID Data Ecosystem2026-03-13 收录
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The deletion of the Staphylococcus aureus 5-bp motif, TATTT, which plays a role in regulating the icaADBC operon, induces excessive biofilm formation. Isolation of the TATTT deletion mutant of FK300 caused several mutants with a peculiar phenotype (FK300delta5bpBm) to autoaggregate upon vortexing. Genome sequencing revealed that these mutants carried mutations in icaB.

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2022-08-03
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