Herpesviral induction of germline transcription factor DUX4 is critical for viral gene expression. Herpesviral induction of germline transcription factor DUX4 is critical for viral gene expression

We describe the role of the cellular transcription factor DUX4 in the regulation of herpesviral gene expression. Overall design: RNA-sequencing was performed from HSV-1 infected 293T cells with and without DUX4 knockout and ChIP-seq. from primary human foreskin fibroblasts infected with HSV-1 and controls,