Gut microbiota analysis associated with hepatocellular carcinoma. Gut microbiota analysis associated with hepatocellular carcinoma

Here we report 16s rRNA data in gut microbiota of hepatocellular carcinoma (HCC) patients with HBV induced HCC (HBVC) and non-HBV induced HCC (NHBVC) compared with healthy volunteers. A total of 2047 operational taxonomic units (OTUs) were identified in the sequence data. Our data shows that the NHBVC patients harbor lower anti-inflammatory bacteria and more pro-inflammatory bacteria, while the HBVC patients harbor more anti-inflammatory bacteria. Overall design: Microbial DNA from fecal samples [healthy control (n=33), NHBVC patients (n=26), HBVC (n=35) was amplified by PCR using universal bacterial primers, and 16S rRNA genes were pyrosequenced.