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Additional file 4: Figures S8-S10. of B cell depletion therapy upregulates Dkk-1 skin expression in patients with systemic sclerosis: association with enhanced resolution of skin fibrosis

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Dkk-1 is not expressed in epidermis (black arrow), appendices (green arrow) and spindle-like cells (red arrows) in the control patient group at baseline (A and B) and follow up biopsies (D and E). Streptavidin biotin peroxidase (A and D × 20, B and E × 400) (ZIP 5018 kb)

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2016-12-14
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