Use of monoclonal antibodies to identify four neutralization immunogens on a common cold picornavirus, human rhinovirus 14.
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The sequence is from the reference cited: Stanway et al.(1984) Nuc Acids Res 12: 7859-7875 [PMID: 6093056]. The epitopic residues in the NIm-IA antigenic site recognized by the mAbs was determined by sequencing variant viruses selected with the mAbs. Variants with mutation of VP1 residue Asp91 to a Glu, His, Ala, Tyr, Val, Asn, or Gly or mutation of residue Glu95 to a Lys or Gly were not neutralized by the mAbs.
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IEDB创建时间：
1986-01-01
