Crystal structure of human Beta secretase complexed with inhibitor
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Crystal structure of human Beta secretase complexed with inhibitor Descriptor: 3-{2-[(5-AMINOPENTYL)AMINO]-2-OXOETHOXY}-5-({[1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)PHENYL PHENYLMETHANESULFONATE, Beta-secretase 1 Authors: Munshi, S, Chen, Z, Kuo, L. Deposit date: 2004-06-17 Release date: 2004-11-09 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases. J.Med.Chem., 47, 2004
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2004-06-17
