Differential gene expression in CNS after scrapie infection
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Differential gene expression in CNS after scrapie infection
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2014-06-01
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Genome-wide transcriptomics identifies an early preclinical signature of prion infection. Genome-wide transcriptomics identifies an early preclinical signature of prion infection
We constructed a searchable genome-wide atlas of mRNA abundance, splicing and editing alterations during the course of disease in prion-inoculated mice. Overall design: Mice were inoculated with prion
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Additional file 4 of The degree of astrocyte activation is predictive of the incubation time to prion disease
Additional file 4. Table S4 Linear fold change for each gene, reported as a ratio between each sample group and normal i.p. female (F) as a control group. The table includes data for four brain region
Figshare2021-05-13 更新50
Protocol S1 - Early Onset Prion Disease from Octarepeat Expansion Correlates with Copper Binding Properties
Statistical analysis using nonlinear regression and Bayesian change point models. These findings provide additional support for the relationship between OR length and onset age, and also reveal eviden
NIAID Data Ecosystem40
MiRNAs identified as differentially expressed in CNS tissues of scrapie infected mice.
MiRNAs which exhibit a trend towards up-regulation; miR-200a, miR-200b, miR-26a, miR-186, miR-331-3p, miR-152, miR-221. *Results from [23].
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Data_Sheet_1_Neurons and Astrocytes Elicit Brain Region Specific Transcriptional Responses to Prion Disease in the Murine CA1 and Thalamus.CSV
Progressive dysfunction and loss of neurons ultimately culminates in the symptoms and eventual fatality of prion disease, yet the pathways and mechanisms that lead to neuronal degeneration remain elus
NIAID Data Ecosystem40
