Results of recommendation extraction from guidelines addressing validity threats in preclinical experiments.

aExplicit endorsement of STAIR [10],[12].bExplicit endorsement Piper et al. [53].CV, threat to construct validity; EV, threat to external validity; IV, threat to internal validity; O, outcome; PROG, research program recommendations; T, treatment; Ŧ, recommendation imported from an endorsed guideline but not otherwise stated in the endorsing guideline; U, units (animals); Δ, recommendation imported from an endorsed guideline and also explicitly stated in the endorsing guideline; Total, all parts of the experiment; X, recommendation explicitly stated in the guideline.NINDS-NIH, US National Institutes of Health National Institute of Neurological Disorders and Stroke.