Transcriptome in Rat Skeletal Muscle 1 month or 3 months after Early Protein Restriction

Transcriptome profiling reveal that myogenic differentiation functions are upregulated while protein catabolism are downregulated as compensatory toward protein restriction, while endo-plasmic reticulum stress are enhanced, inducing undesired apoptosis.转录组谱分析（Transcriptome profiling）结果显示，在蛋白质限制条件下，肌源性分化功能上调，而蛋白质分解代谢作为代偿机制被下调；与此同时，内质网应激（endoplasmic reticulum stress）被激活，进而诱导了非预期的细胞凋亡。