Association (Kon) and dissociation (Koff) rate constants for purified MAb DB81 were measured by surface plasmon resonance. The Kd was calculated as Koff\\Kon.
*IC50 values reflect concentration of Tfab required to compete 50% of saturating Tmab IgG. Errors are standard deviations from technical triplicates. In vitro binding affinity of Tfab and Tmab.
Cryo-EM Structure of CAP256-VRC26.25 Fab bound to HIV-1 Env trimer CAP256.wk34.c80 SOSIP.RnS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-ace