EBF1 Promotes Triple-Negative Breast Cancer by Surveillance the HIF1A Pathway
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
Genome-wide mapping of the EBF1 transcriptional regulatory network revealed that EBF1 drives TNBC tumorigenicity by assembling a transcriptional complex with HIF1A that fine-tunes the expression of HIF1A targets via suppression of p300 activity. EBF1 therefore holds the HIF1A activity in check to keep the mitochondria homeostasis thus avert extensive mitophagy-induced cell death.
创建时间：
2021-07-08
