Structure of an ML-IAP/XIAP chimera bound to a peptidomimetic
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Structure of an ML-IAP/XIAP chimera bound to a peptidomimetic Descriptor: (3R,6R,9AR)-2,2-DIMETHYL-6-[(N-METHYL-L-ALANYL)AMINO]-N-(3-METHYL-1-PHENYL-1H-PYRAZOL-5-YL)-5-OXO-2,3,5,6,9,9A-HEXAHYDRO[1,3]THIAZOLO[3,2-A]AZEPINE-3-CARBOXAMIDE, 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Fairbrother, W.J, Franklin, M.C. Deposit date: 2006-08-18 Release date: 2006-09-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs. Acs Chem.Biol., 1, 2006
创建时间：
2006-08-18
