Parameters of oral enrofloxacin in healthy and infected broilers (mean ± S.E.M., n = 10).

*P<0.05, ** P<0.01 significant difference vs. healthy broliers. Ke:,elimination rate constant; Ka, absorption rate constant; t1/2a, the absorption half-life; t1/2e, the elimination half-life; Tmax, the time to reach peak concentration; Cmax, the peak concentration; AUC0-12h, the area under the plasma concentration-time curve from zero to 12h; V/F, volume of distribution/F, where F is the faction of dose absorbed; Cl/F, Clearance/F, where F is the faction of dose absorbed.