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Genome-wide mapping of ssDNA in human. Homo sapiens

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NIAID Data Ecosystem2026-03-07 收录
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We combined chemical and enzymatic techniques to map single-stranded DNA (ssDNA) across the mammalian genome by high-throughput sequencing (ssDNA-Seq). The new approach makes use of KMnO4 treatment, which modifies ssDNA in living cells by oxidizing pyrimidine bases with a marked preference for exposed thymidine residues.

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2013-03-21
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