Podocytes, highly differentiated glomerular epithelial cells, are essential for the maintenance of glomerular filtration barrier. Podocyte dysfunction in podocytes is a major determinant of proteinuri

NIAID Data Ecosystem30

Microarray Analyses of Glucocorticoid and Vitamin D3 Target Genes in Differentiating Cultured Human Podocytes

细胞分子机制

激素靶基因分析

Glomerular podocytes are highly differentiated epithelial cells that are key components of the kidney filtration units. Podocyte damage or loss is the hallmark of nephritic diseases characterized by s

Figshare2016-01-18 更新20

Transcriptome-wide identification of CELF2 functional targets in T cells. Homo sapiens

细胞分子机制

RNA剪接调控

CELF2 is a critical regulator of alternative splicing during T cell development and during stimulation-induced T cell activation. Here we utilize RNA-seq to globally profile the functional targets of

NIAID Data Ecosystem30

Gene expression comparison between the murine T-cell hybridoma 6-13-64 ICOS(-) population and ICOS(+) population

细胞分子机制

差异基因表达分析

ICOS (Inducible Costimulator) is a T cell costimulatory molecule. We found that the cloned T-cell hybridoma 6-13-64 consists of two populations, ICOS expressing and non-expressing. The aim of this stu

NIAID Data Ecosystem30

Agonism of AlkP expression, cell proliferation and gene transcription.

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