Experimental design and numbers of animals per group.

Control = spontaneously breathing, non-ventilated mice; CM = conditioned medium of iPSCs; EBD = Evans blue dye; TEM = transmission electron microscopy; IHC = immunohistochemical stain; iPSCs = induced pluripotent stem cells; MEF = mouse embryonic fibroblast; MIP-2 = macrophage inflammatory protein-2; MPO = myeloperoxidase; NF-κB = nuclear factor-κB; NKRF = NF-κB repressing factor; ROS = reactive oxygen species; PBS = phosphate-buffered saline; Scam = nontargeting scrambled siRNA; siRNA = short interfering RNA; VT = tidal volume.