Gene expression in PC3 cells(human prostate cancer cell line) upon HIC1 knockout
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141642
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To explore the role of HIC1 deletion in regulating prostate cancer(PCa) microenvironment development, Human Gene Expression Microarrays were searched for altered genes upon HIC1 knockout expression in PC3 cells. According to fold-change screening between HIC1-knockout and its respective control cells, both up-regulated and down-regulated genes were shown. Human PCa cell line PC3 was transfected with Lenticas9-blast and the sgRNA expression plasmid Lentiguid-puro (sgRNA targeting HIC1 and respective control). HIC1-knockout cells were respectively noted as PC3 sgHIC1. Their respective control cells were respectively noted as PC3 Ctrl.
创建时间:
2019-12-12



