Data_Sheet_1_Chemical Proteomics-Guided Identification of a Novel Biological Target of the Bioactive Neolignan Magnolol.PDF
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https://figshare.com/articles/dataset/Data_Sheet_1_Chemical_Proteomics-Guided_Identification_of_a_Novel_Biological_Target_of_the_Bioactive_Neolignan_Magnolol_PDF/7692614
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资源简介：
Understanding the recognition process between bioactive natural products and their specific cellular receptors is of key importance in the drug discovery process. In this outline, some potential targets of Magnolol, a natural bioactive compound, have been identified by proteomic approaches. Among them, Importin-β1 has been considered as the most relevant one. A direct binding between Magnolol and this nuclear chaperone has been confirmed by DARTS and molecular docking, while its influence on Importin-β1 translocation has been evaluated by in vitro assays.
创建时间：
2019-02-08
