Expression changes after loss of Dot1l in murine MLL-AF9 leukemia cells

ChEBI2011-09-12 更新2026-07-21 收录

白血病机制研究

表观遗传学实验

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Expression changes after loss of Dot1l in murine MLL-AF9 leukemia cells

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2011-09-12

The C-terminus of CBFß-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis.

白血病机制研究

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The C-terminus of CBFß-SMMHC, the fusion protein produced by a chromosome 16 inversion in acute myeloid leukemia subtype M4Eo, contains domains for self-mulimerization and transcriptional repression,

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Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [BcorKrasRNA-seq]

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NIAID Data Ecosystem50

TF ChIP-seq from MEL cell line (ENCSR705HGT)

转录因子结合位点分析

表观遗传学实验

USF1 ChIP-seq mouse MEL produced by the Snyder lab For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_

NIAID Data Ecosystem40

MOESM2 of Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

DNA甲基化分析

表观遗传学实验

Additional file 2: Table S8. Primer sequences for bisulfite sequencing of the validated CpGs.

NIAID Data Ecosystem60

Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]. Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]

造血表观遗传学

白血病机制研究

Cellular differentiation-trajectories require extensive alterations in chromatin structure and function, elicited by a diverse array of chromatin-factors (CFs). Using haematopoiesis as a model-system,

NIAID Data Ecosystem50

Expression changes after loss of Dot1l in murine MLL-AF9 leukemia cells

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