Online Supplementary materials

<b>Title:</b> Genetically predicted lifelong circulating 25(OH)D levels are associated with serum calcium levels and kidney stone risk. <b>Running head: </b>vitamin D, calcium and kidney stone<b></b> <b>Authors: </b>Zhongyu Jian^a,b, Yu Huang^c, Yazhou He^d, Xi Jin^a, Hong Li^a, Sheyu Li^e,f,g*, Kunjie Wang^a,*. <b>Affiliations: </b> <b>^a</b>Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu, People's Republic of China. ^bWest China Biomedical Big Data Center, Sichuan University, Chengdu, People's Republic of China. ^cGuangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. ^dWest China School of Public Health and West China Fourth Hospital, Sichuan University, China. ^eDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China. ^fChinese Evidence-based Medicine Center, Cochrane China Center and MAGIC China Center, West China Hospital, Sichuan University, Chengdu, China. ^gEngineering Research Center of Medical Information Technology, Ministry of Education, West China Hospital, Sichuan University, Chengdu, China. <b>*Corresponding author: </b>Kunjie Wang; Mailing address: Department of Urology, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu City, Sichuan Province, PR China. Telephone number: [phone]. E-mail address: [e-mail]. Sheyu Li; Mailing address: Department of Endocrinology and Metabolism, Chinese Evidence-based Medicine Center, Cochrane China Center and MAGIC China Center, Engineering Research Center of Medical Information Technology, Ministry of Education, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu City, Sichuan Province, PR China. E-mail address: [e-mail]. <b>Keywords: </b>Mendelian randomization; kidney stone disease; nephrolithiasis; vitamin D.<b></b>