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Chromatin profiling in HT22 hippocampal cells

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NIAID Data Ecosystem2026-05-26 收录
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We conducted genome-wide analysis of KMT2D binding sites in a hippocampal cell line to define KMT2D-dependent functions in neuronal context Overall design: ChIP-seq in wild-type HT22 cells and HT22 cells with CRISPR-Cas9 mediated deletion of the KMT2D enzymatic SET methyltransferase domain, comparing KMT2D-pulldown and input controls

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2019-02-13
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