Correct chromosome segregation is essential in order to prevent aneuploidy. To segregate sister chromatids equally to daughter cells, the sisters must attach to microtubules emanating from opposite sp
Crystal structure of human Survivin bound to histone H3 phosphorylated on threonine-3 (C2 space group). Descriptor: Baculoviral IAP repeat-containing protein 5, N-terminal fragment of histone H3, ZINC
Spliceosome machinery mutations are common early mutations in myeloid malignancies, however effective targeted therapies against them are still lacking. In the current study, we used an in vitro high-