Random Fragments Classification of Microbial Marker Clades with Multi-class SVM and N-Best Algorithm

Microbial clades modeling is a challenging problem in biology based on microarray genome sequences, especially in new species gene isolates discovery and category. Marker family genome sequences play important roles in describing specific microbial clades within species, a framework of support vector machine (SVM) based microbial species classification with N-best algorithm is constructed to classify the centroid marker genome fragments randomly generated from marker genome sequences on MetaRef.