Germinal centers (GCs) are the primary site where B cells undergo affinity maturation, the process whereby the average affinity of antibodies increases with time after immunization.To investigate the

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GC B cell RNAseq. GC B cell RNAseq

Following infection or vaccination, activated B cells at extrafollicular sites or within germinal centers (GCs) undergo vigorous clonal proliferation. Proliferating lymphocytes have been shown to unde

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Transcriptome analysis of mouse WT and CD22 KO GC B cells

Germinal centres (GC) are specialized sites where B cells expand and diversify their antibody genes through somatic hypermutation. GC B-cells are routinely identified through distinct changes on their

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Csk KO GC B cell