Expression profiling of control and Yap/Taz conditional knockout mouse incisor labial cervical loops. Mus musculus
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To understand expression changes caused by deletion of Yap and Taz in the mouse incisor labial cervical loops, we performed microarray analysis. As 100% CreER recombination was not possible, mutant samples would have contained some wild type cells. Nonetheless, these results identified genes that are up- or down-regulated in the absence of Yap and Taz and led us to uncover changes in cell differentiation, as well as mTOR signaling. Overall design: Total RNA extracted from isolated labial cervical loops of 8 weeks old Yap/TazcKO mice were compared with control samples.
创建时间：
2016-09-20
