Crystal structure of PDE4D catalytic domain complexed with compound 17a
收藏Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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Crystal structure of PDE4D catalytic domain complexed with compound 17a Descriptor: (~{E})-4-[8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-9-oxidanyl-6-oxidanylidene-pyrano[3,2-b]xanthen-5-yl]oxybut-2-enoic acid, Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D, MAGNESIUM ION, ... Authors: Huang, Y.-Y, He, X, Luo, H.-B. Deposit date: 2021-06-11 Release date: 2021-10-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.10001966681 Å) Cite: Mangostanin Derivatives as Novel and Orally Active Phosphodiesterase 4 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis with Improved Safety. J.Med.Chem., 64, 2021
创建时间：
2021-06-11
