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One-Pot Multicomponent Cascade Reaction of <i>N,S</i>-Ketene Acetal: Solvent-Free Synthesis of Imidazo[1,2-<i>a</i>]thiochromeno[3,2-<i>e</i>]pyridines

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Unprecedented imidazo[1,2-a]thiochromeno[3,2-e]pyridines have been synthesized via a three-component cascade reaction under solvent-free conditions. This one-pot transformation involving multiple steps and not requiring the use of transition metal catalysts constructs three new C–C bonds, two C–N bonds, one C–S bond, and three new rings with all reactants efficiently utilized.

创建时间:
2016-02-20
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