Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145022

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Here we describe a mouse model of mesothelioma with combined deletion of Bap1, Nf2, and Cdkn2ab that shows rapid onset and recapitulates human mesothelioma including its response to the standard treatment. This autochthonous model should be attractive for testing cancer immunotherapies. mRNA profiles of BNC and NC mesothelioma

创建时间：

2023-06-14