Effector-induced allosteric transitions in cytochrome P450 3A4 (CYP3A4) were investigated by luminescence resonance energy transfer (LRET) between two SH-reactive probes attached to various pairs of d

NIAID Data Ecosystem40

Cumulative Effect of Phosphorylation of pRB on Regulation of E2F Activity

细胞周期调控

磷酸化机制

The product of the retinoblastoma susceptibility gene, pRB, is a nuclear phosphoprotein that controls cell growth by binding to and suppressing the activities of transcription factors such as the E2F

PubMed Central20

Condensin chromatin association is regulated by the combined actions of SMC head and hinge engagement and phosphorylation

染色体调控

磷酸化机制

The SMC condensin complex is essential for normal mitotic chromosome structure in eukaryotes. Here we undertake a comprehensive analysis of the importance of the condensin ATP binding and hydrolysis,

NIAID Data Ecosystem50

Pseudomonas fluorescens PhoX in complex with the substrate analogue AppCp

蛋白质复合物结构解析

磷酸化机制

Pseudomonas fluorescens PhoX in complex with the substrate analogue AppCp

NIAID Data Ecosystem40