Estimation of heritability (%) from identified SNPs with nominal P-value 1.

1h2(g), heritability of additive genetic variance; h2 (gxe), heritability of GxE interaction; SE, standard error.2P-values were adjusted for age, sex, study center, kinship, and population structure.3P-values were adjusted for age, sex, body mass index, study center, kinship, and population structure.495th percentile for the P-value and heritability estimate from the 1000× GCTA bootstrap analysis for each trait. In each case, the GCTA GxE P-value falls below the 95th percentile indicating that these results are highly unlikely to be obtained merely by chance.