A major difficulty in treating cancer is the inability to differentiate between normal and tumor cells. The immune system differentiates tumor from normal cells by T cell receptor (TCR) binding of tum
The limited tissue penetration depth of optical probes based on 2-(2′-hydroxyphenyl)-4(3H)-quinazolinone (HPQ) hindered dynamic monitoring of the actual distribution and metabolism of them in deep tis
IntroductionPancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant neoplasms, as many cases go undetected until they reach an advanced stage. Integrin αvβ6 is a cell surface r
Gangliosides are sialic acid-containing glycolipids expressed on plasma membranes from nearly all vertebrate cells. The expression of ganglioside GD3, which plays essential roles in normal brain devel
Optical imaging and diagnostic applications employing fluorescence dyes and molecular probes is having increased impact in both research and clinical settings. The rapid evolution of instrument manufa